Preimplantation Genetic Testing (PGT) is a specialized genetic analysis performed on embryos before implantation during an IVF cycle. Its purpose is to identify healthy embryos, increasing the chances of a successful pregnancy and a healthy baby.
Why choose PGT?
PGT enables the detection of genetic and chromosomal abnormalities in embryos before transfer. This allows:
- Higher IVF success rates
- Lower risk of miscarriage and genetic syndromes
- Reduced need for prenatal diagnosis or pregnancy termination
- Increased confidence in single embryo transfer (SET)
Types of Preimplantation Testing
At Reprogenetica, we offer a full range of PGT services through collaborations with internationally accredited laboratories:
PGT-A (Aneuploidy Screening)
Detects chromosomal abnormalities such as trisomies (e.g., T21, T18, T13) which are linked to miscarriage or genetic disorders. Recommended especially for:
- Women over the age of 35
- Couples with recurrent pregnancy loss
- Repeated failed IVF attempts
- Egg or sperm donation cycles
PGT-M (Monogenic Disease Testing)
Used when prospective parents are carriers of specific single-gene disorders (e.g., Cystic Fibrosis, Thalassemia, Tay-Sachs Disease). It ensures that only embryos free of the disorder are transferred.
PGT-SR (Structural Rearrangement Testing)
Designed for carriers of known chromosomal rearrangements (e.g., translocations, inversions). It helps identify embryos with a normal chromosomal structure, minimizing the risk of miscarriage or abnormalities.
FAQ
The Process in Simple Steps
- IVF cycle: Embryos are created through in vitro fertilization
- Embryo biopsy: Usually at the blastocyst stage (Day 5 or 6)
- Genetic analysis: Performed at a certified specialized laboratory
- Embryo selection: Based on genetic integrity and implantation potential
- Embryo transfer: The healthiest embryo is transferred to the uterus
Technology & Reliability
Reprogenetica uses cutting-edge genetic technologies such as Next Generation Sequencing (NGS) to ensure high accuracy and reliability.
Is PGT right for me?
PGT is especially beneficial for:
- Couples with repeated IVF failure or miscarriage
- Women of advanced maternal age
- Families with a history of genetic conditions
- Known carriers of monogenic disorders
Risk of embryos carrying chromosomal abnormalities
Τεχνολογία & Αξιοπιστία
Η Reprogenetica αξιοποιεί τις πλέον σύγχρονες τεχνικές γενετικής ανάλυσης, όπως Next Generation Sequencing (NGS), για υψηλή ακρίβεια και αξιοπιστία αποτελεσμάτων.